[2] It can be used both to treat and to prevent heart-related chest pain; however, it is generally less preferred than beta blockers or calcium channel blockers. Herbal supplements and heart medicines may not mix - Mayo Clinic St. John's wort. Some of these interactions can be life-threatening. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Imdur (isosorbide mononitrate) Extended Release and Isordil (isosorbide dinitrate) are vasodilators indicated for the prevention of angina pectoris due to coronary artery disease.. Side effects of Imdur and Isordil that are similar include headache and dizziness.. Side effects of Isordil that are different from Imdur include weakness and skin changes such as redness, tingling, or warmth. Can cause dizziness, especially when you change positions, Interacts with erectile dysfunction medications. Isosorbide mononitrate | Drugs | BNF | NICE Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. The use of the Truven Health products is at your sole risk. The effects of this exposure on a nursing infant are unknown. Accessed Sept. 7, 2022. Swallow the tablet/capsule whole - do not chew or crush it before you swallow. What side effects can this medication cause? We comply with the HONcode standard for trustworthy health information. Isosorbide mononitrate (Monoket) may interact with certain medications or supplements. Alcohol will increase the risk of you experiencing side-effects such as feeling dizzy and light-headed. Isosorbide mononitrate Interactions - Drugs.com Discuss the risks and benefits with your doctor. Browse all drugs on eHealthMe. DUMQOL (DUtch Mononitrate Quality of Life) Study Group. Portions of this document last updated: Feb. 01, 2023. Review/update the Clin Res Cardiol. Get emergency help immediately if any of the following symptoms of overdose occur: bulging soft spot on the head of an infant, change in the ability to see colors, especially blue or yellow, feeling of constant movement of self or surroundings. Last Revised - 09/15/2019. Both versions of isosorbide mononitrate (Monoket) contain the same active ingredient. The list below does not include all possible drug interactions with isosorbide mononitrate (Monoket). What special precautions should I follow? It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. Isosorbide Mononitrate - Uses, Side Effects, and More - WebMD [2] The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Thirty percent of the patients never experienced headache from the given dosages. Contact your provider right away if you feel as if you are going to pass out and are experiencing an irregular heartbeat, nausea, vomiting, changes in vision, more sweating, or cold and clammy skin. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. other information we have about you. Danshen can interact strongly with some heart medicines, such as: Evening primrose may raise your risk of bleeding if you also take a blood thinner, such as: Garlic may raise your risk of bleeding if you also take a blood thinner, such as: Ginkgo biloba may raise your risk of bleeding if you also take a blood thinner, such as: If you take ginseng with warfarin, it may lessen how well warfarin works. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as isosorbide dinitrate, nitroglycerin); or if you have any other allergies. 2017; doi:10.1016/j.jacc.2016.11.078. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Do not take more or less of it or take it more often than prescribed by your doctor. See also: nitroglycerin side effects in more detail. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. This is called tolerance, and it cannot be fixed by raising the dose of the medication. Some conditions may become worse when the drug is suddenly stopped. The site is secure. Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. Things to remember when you fill your prescription. Isosorbide mononitrate (Monoket) can cause headaches, dizziness, or lightheadedness. In the remainder of them there was a highly significant time effect: the overall numbers of headache attacks in the first period of active treatment versus the second were 2,380 vs 1,400 (P < 0.003). Then, there was a two-week placebo washout, after which the alternative treatment was given. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. Isosorbide-5-mononitrate ISMN usually begins acting within 30 minutes and its effects last six to eight hours. The extended-release capsule usually is taken once daily. US residents can call their local poison control center at 1-800-222-1222. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Lifestyle changes such as dietary changes, exercise, and not smoking may help this drug work better. Daily headaches are a common side effect. Cao HY, Wu HD, Song ZK, Tang ML, Yang S, Liu Y, Qin L. Pan Afr Med J. If you suffer headaches when taking Isosorbide mononitrate, be patient. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. These headaches may be a sign that the medication is working as it should. View World Anti-Doping Agency classifications, Prevention of Thromboembolism in Atrial Fibrillation, Prosthetic Heart Valves - Thrombosis Prophylaxis, Prosthetic Heart Valves - Mechanical Valves - Thrombosis Prophylaxis, Revascularization Procedures - Prophylaxis. Use of herbal products and potential interactions in patients with cardiovascular diseases. You may opt-out of email communications at any time by clicking on Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Isosorbide tablets are also used with other medications to treat heart failure. Egton Medical Information Systems Limited. In: Textbook of Natural Medicine. Isosorbide mononitrate (Monoket) is available as both a immediate-release (IR, short-acting) and extended-release (ER, long-acting) tablet. There are 7 disease interactions with isosorbide mononitrate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. What is the difference between the immediate-release (IR) and extended-release (ER) versions of isosorbide mononitrate (Monoket)? It works by . Severe postural hypotension with light-headedness and dizziness is frequently observed after the consumption of alcohol. Isosorbide mononitrate - UpToDate Isosorbide dinitrate (Isordil): Basics, Side Effects & Reviews - GoodRx Do not take a double dose to make up for a missed one. This content does not have an English version. Copyright 2023 IBM Watson Health. Our clinical information meets the standards set by the NHS in their Standard for Creating Health Content guidance. An official website of the United States government. Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication. Accessed Sept. 7, 2022. Now, youll enjoy a streamlined experience created specifically for healthcare providers. Do not try to change the times or the way that you take isosorbide in order to avoid headaches because then the medication may not work as well. Try our Symptom Checker Got any other symptoms? Accessed Sept. 7, 2022. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. Aspirin relieves pain and inflammation and helps to thin the blood. For these reasons, before you start taking isosorbide mononitrate it is important that your doctor knows: Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. As precautionary measure, breast-feeding should be discontinued during treatment with isosorbide mononitrate. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. Each day, take the first dose when you wake up, then take the second dose 7 hours later. (1) Starting on a low dosage was associated with a reduced frequency and severity of headache and did not notably influence the beneficial effect on angina pectoris. Natural Medicines. Isosorbide: MedlinePlus Drug Information Advertising revenue supports our not-for-profit mission. Unable to load your collection due to an error, Unable to load your delegates due to an error. Isosorbide mononitrate (Monoket) can cause your blood pressure to drop somewhat. Isosorbide mononitrate helps to prevent angina chest pain from developing. Consult your doctor for more details. Enter other medications to view a detailed report. 1998 Oct;61(10):577-83. Almost 70% of older adults use them. The tablet usually is taken two or three times daily. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Along with its needed effects, a medicine may cause some unwanted effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Isosorbide mononitrate dose and side-effects info | Patient If you miss a dose, take it as soon as you remember. Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Some products have ingredients that could worsen your heart failure. Synthroid (levothyroxine) Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D3 (cholecalciferol) Isosorbide mononitrate disease interactions There are 7 disease interactions with isosorbide mononitrate which include: AMI anemia hemodialysis hypotension intracranial pressure hypertrophic cardiomyopathy glaucoma If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. Heres what you need to know about alcohol and blood pressure including how alcohol can interact with your blood pressure medications. Usually avoid combinations; use it only under special circumstances. Isosorbide mononitrate (Monoket) can cause some serious health issues. Below is the list of medicines, which contains Isosorbide Mononitrate as ingredient. If you do not remember until your next dose is nearly due, then leave out the forgotten dose and take your next dose when it is due. It is best not to drink alcohol while you are on isosorbide mononitrate. May also be prescribed off label for Esophageal Spasm. Using this medicine with any of the following medicines is not recommended. This site complies with the HONcode standard for trustworthy health information: verify here. The extended-release tablet usually is taken once daily in the morning. This medicine is available only with your doctor's prescription.